HMGCR and breast cancer: Cholesterol biosynthesis genes, including NSDHL, sterol C4-methyl oxidase-like (SC4MOL), farnesyl-diphosphate farnesyltransferase 1 (FDFT1), 3-hydroxy-3-methylglutaryl-CoA synthase 1 (HMGCS1), 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), emopamil-binding protein (EBP), and 7-dehydrocholesterol reductase (DHCR7) are highly expressed in breast cancer cells [22].