AFP and neoplasm: Among those with RI undergoing non-curative treatment, serum AFP ≥20 ng/mL (HR: 1.648, p < 0.001), multiple tumors (HR: 1.217, p < 0.001), tumor size >3 cm (HR: 1.914, p < 0.001), vascular invasion (HR: 1.662, p < 0.001), distant metastasis (HR: 1.395, p = 0.021), presence of ascites (HR: 1.249, p = 0.033), performance status 1–2 (HR: 1.314, p = 0.025), performance status 3–4 (HR: 1.876, p < 0.001), ALBI grade 2 (HR: 1.659, p < 0.001), and ALBI grade 3 (HR: 2.081, p < 0.001) were associated with poor survival in the Cox model (Table 5).