TB patients with high DNA methylation levels over +28532 CpG site of the WIPI2 gene (>20%, n = 28) had lower one-year survival (all-cause mortality rate 17.85% versus 0%, p = 0.007 by log-rank test, Figure 3b) than those with low methylation levels (≤20%, n = 36). This evidence concerns the gene WIPI2 and tuberculosis.