In triple negative breast cancer cells, garcinol was reported to sensitizes tumor cells to Taxol, which was mediated via suppression of caspase-3/cytosolic CA2+-independent phospholipase A2 (iPLA2) and NF-κB/Twist-related protein 1 (Twist1) pathway in mouse 4T1 breast tumor model [21]. The gene discussed is TWIST1; the disease is breast neoplasm.