Although it is uncertain whether mitochondria could have a function in this process, recent evidence could bring new findings on novel functions that impact on ferroptosis such as the status of ferroptosis suppressor protein 1 (FSP1) in the control of the reduced co-enzyme Q10 [191], which may potentially highlight the role of ferroptosis as a novel attractive therapeutic concept in cancer biology [192,193]. The gene discussed is AIFM2; the disease is cancer.