CXCL8 and systemic sclerosis: In particular, the pro-oxidant environment induced significant increases in IL-8 gene expression in healthy (control (c) vs. H2O2: IL-8, 0.1 ± 0.0 vs. 0.3 ± 0.0, p < 0.01) or in SSc fibroblasts (c vs. H2O2: IL-8, 0.1 ± 0.0 vs. 0.4 ± 0.2, p < 0.01).