HMGA2 and lipoma: In most lipomas and pulmonary chondroid harmatomas, chromosomal translocations have breakpoints that preferentially cluster in the third intron of the HMGA2 gene to yield either oncogenic truncated forms of HMGA2 mRNA transcripts containing exons 1–3 and lacking the 3’ untranslated region (3’ UTR), and/or chimeric fusion transcripts co-joining truncated HMGA2 DNA binding domains to up- or downstream transcriptional regulatory sequences [51,52].