TNFRSF10B and cancer: For example, Abdelghany et al. [188] conjugated an antibody-targeting death receptor 5 (DR5), a cell surface apoptosis-inducing receptor upregulated in various types of cancer cells, on the surface of chitosan/alginate nanoparticles loaded with the hydrophilic photosensitizer meso-tetra(N-methyl-4-pyridyl)porphyrin tetra-tosylate (TMP).