Several studies in systemic autoimmune and chronic inflammatory diseases, e.g., systemic lupus erythematosus (SLE), rheumatoid arthritis, or chronic lung diseases describe increased sCD62L serum levels [35,36,45], together with other elevated adhesion molecules, such as ICAM-1 and VCAM-1 [46,47,48]. The gene discussed is ICAM1; the disease is systemic lupus erythematosus.