To explore the possibility that GAPDH dysfunction represents a universal feature of oncocytic lesions, irrespective of their origin, we tested a control cohort of renal epithelial neoplasms with prominent oncocytic features (oncocytoma and oncocytoid chromophobe carcinoma); none showed the distinctive GAPDH phenotypes we described herein for salivary gland Warthin tumors, indicating that this expression pattern is likely specific for Warthin tumors. Here, GAPDH is linked to oncocytic adenoma.