RT-qPCR analysis show that ADAM10, ARMC8, COMMD8, EEA1 and PPM1B were expressed at similar levels in prostate cancer cells transfected with ZBTB38 and control siRNAs suggesting that these genes are not regulated by ZBTB38, but rather co-regulated by a common upstream factor and/or pathway (Figure S1). The gene discussed is EEA1; the disease is Familial prostate cancer.