To further study the biological alterations and pathways associated with ZBTB38 expression status, we identified differentially expressed genes (p < 0.001) between localised tumours expressing low levels of ZBTB38 and tumours expressing high levels of ZBTB38. To do that, we compared the whole-genome expression profile of the localised tumours expressing low levels of ZBTB38 (1st quartile) and tumours expressing high levels of ZBTB38 (4th quartile) in four independent cohorts from different research centres [12,14,48,50]. Here, ZBTB38 is linked to neoplasm.