In addition, high expression of ITGB1 and low expression of p53 has been found to act as adverse prognostic factors in NSCLC.35 P53‐induced miR‐30e‐5p inhibits cell metastasis in colorectal cancer by targeting ITGB1.36 All these findings support our conclusion that miR‐374b inhibits the progression of NSCLC by downregulating ITGB1 and promoting p53 expression. Here, TP53 is linked to colorectal cancer.