A Multiple logistic regression model, including all the significant baseline variables (P<0.05) predictive of AF, showed that RHI (OR=5.94; 95% CI = 0.93- 20.78; p = 0.053), IL- 18 (OR = 1.01; 95% CI = 1-1.019; p = 0.042), TNF α (OR = 5.1; 95% CI = 1.35-19.18; p = 0.016), sIL-2Rα (OR= 1.02; 95% CI = 1.007-1.038; p = 0.005) and hypertension (OR = 6,8; 95% CI = 2.1-20.98; p = 0.003) were independently associated with the arrhythmia (Table 3). The gene discussed is TNF; the disease is cardiac arrhythmia.