Thus far, 309 disease-associated variants in the CHM gene have been identified in patients with choroideremia, including 84 missense/nonsense variants, 51 splicing variants, 71 small deletion variants, 26 small insertion variants, 10 small indel variants, 55 gross deletion variants, 3 gross insertion variants, 4 regulatory variants, and 5 complex rearrangement variants (https://www.hgmd.cf.ac.uk, updated 2019.3). This evidence concerns the gene CHM and choroideremia.