Moreover, FOXK2, one of the two members of FOXK family, which collaborated with FOXK1 and showed the similar capability in a few physiological and pathological processes (19, 20, 33), has been demonstrated to change the phosphorylated status of AKT and exert oncogenic function in hepatocellular carcinoma (34). The gene discussed is FOXK1; the disease is hepatocellular carcinoma.