rs4950928 SNP genotype distribution did not differ between tumor grades [p = 0.29 (Fisher's exact test)] but the rs4950928 SNP was significantly associated with lower YKL-40 plasma levels (CC vs. GC, p = 0.0019; CC vs. GG, p = 0.01) (Figure 2) in Cohort 1. This evidence concerns the gene CHI3L1 and neoplasm.