To evaluate the role of c-Myc in pancreatic cancer cells, siRNA targeting c-Myc (si-c-Myc) and siRNA negative control (si-NC) were transfected into PANC-1 cells, and the c-Myc overexpression vector (pcDNA-c-Myc) and empty vector (pcDNA) were transfected into SW1990 cells. The gene discussed is MYC; the disease is familial pancreatic carcinoma.