The derivatives 2-((4-(3,5-Dimethoxystyryl)phenylamino)methyl)-4-(dimethylamino)phenol (5 days) and (E)-5-(4-(5-(Dimethylamino)-2-hydroxy benzyl amino)styryl)-benzene-1,3-diol (10 days) were the lead compounds for AD treatment because they significantly inhibited Aβ aggregation, presented antioxidant activity and moderate acetylcholinesterase inhibition. Here, ACHE is linked to Alzheimer disease.