GPT and liver disorder: In contrast, for HBV monoinfection, TDF is prescribed only for a subset of patients, based on algorithms that incorporate assessment of the patient (age and sex), virologic status (HBV DNA viral load) and the presence of underlying fibrotic or inflammatory liver disease (ALT, elastography score, ultrasound appearance, biopsy results).14, 15, 16 WHO targets for 2030 aim for 90% of HBV cases to be diagnosed, and for 80% of those eligible for treatment to be receiving it.17