PRKG1 and chronic kidney disease: A major role for CDPK1, however, is not supported by our cKD data that showed sensitization to MMV030084 upon reduced expression of PKG, but not of CDPK1 or AAT, coupled with our finding that the IC50 for MMV030084 was equivalent against a CDPK1T145M gatekeeper mutant line (Bansal et al., 2018) compared with its parental control.