TGFB1 and neoplasm: Tumor cells can however acquire a reduced TGF‐β sensitivity as a result of downstream mutations in the signaling pathway,7 meaning that their growth is no more inhibited by increased TGF‐β concentrations.8 Such tumor cells can benefit from a high TGF‐β concentration in their surrounding because it limits the growth of normal cells and facilitates the tumor to infiltrate healthy tissue.