TGFB1 and cancer: αvβ6 Integrin expression and ‐signaling is thus an integral part of the TGF‐β‐mediated cell communication mechanism controlling tissue development and homeostasis, whose dysregulation is related to a wide variety of diseases.3 Overexpression of αvβ6 integrin has particularly interesting implications in terms of cancer.6 For example, TGF‐β acts as a growth suppressor by regulating the transcription of certain growth‐promoting genes.