HSPA1A and rheumatoid arthritis: However, these observations are not consistent with previous pre-clinical reports that had shown that artificial immunization with highly conserved bacterial and/or murine Hsp70 peptides could be regarded as a potential treatment target for RA via induction of the antigen-specific Treg cells (van Herwijnen et al. 2012; Tukaj and Kaminski 2019).