TG and hypothyroidism: Case studies have been published regarding the application of acupuncture in patients with hypothyroidism; they have shown effectiveness in treatment of thyroid dysfunction.[12–14] Herbal medicines have been applied to patients with hypothyroidism, and have been successful for improvement of edema, nocturnal enuresis, fatigue, and anorexia.[15] However, there have been no clinical trials regarding the effects of CAM (eg, herbal medicine and acupuncture) on hypothyroidism and thyroid hormone release.