Our results suggest that pS134-GR promotes basal TNBC cell survival and TGFβ1-induced migration/invasion even in the absence of exogenously added GR ligands, but rather in response to intrinsic or TME stressors; a pS134-GR gene signature distinct from that induced by Dex [12] predicts poor outcome across all breast cancer subtypes. The gene discussed is TGFB1; the disease is breast cancer.