Genes that contribute to FTD include: C9ORF72, FUS, VCP, TDP–43, MAPT/tau, CHMP2B, PGRN, TBK1, and TMEM106B (reviewed in [95]), thus there is overlap with other neurodegenerative diseases including: ALS (C9ORF72, FUS, VCP and TDP–43), AD (tau) and PD (tau). This evidence concerns the gene C9orf72 and neurodegenerative disease.