Similarly, prolonged survival were also observed in the case of encapsulated Inducible nitric oxide synthase (iNOS) expressing cells within alginate microcapsules in DLD-1 human colon adenocarcinoma xenograft models, while a curative outcome was obtained in the case of SKOV-3 ovarian carcinoma cell line [18,20]. Here, NOS2 is linked to colon adenocarcinoma.