Using a single YM155-adapted neuroblastoma cell line, we identified increased ABCB1 (also known as P-glycoprotein or MDR1) expression, decreased SLC35F2 (solute carrier family 35 member F2) expression, decreased survivin expression, and loss-of-p53 function as potential markers of resistance formation to YM155 [16]. The gene discussed is TP53; the disease is neuroblastoma.