We found that COL12A1 was related with a significant target network of kinases including CSNK1A1L, CSNK1G2, and CSNK1D, miRNAs including MIR‐19A/B, MIR‐105, and MIR‐516‐3P, and transcription factors including SOX9, IK2, and CEBP in CRC. This evidence concerns the gene CSNK1A1L and colorectal carcinoma.