CD8A and neoplasm: The benzoporphyrin-containing nMOF not only induced the apoptosis of 4T1 murine breast cancer cells but also stimulated a strong increase in the number of tumor-infiltrating CD8+ and CD4+ T cells, and combining it with an antibody against PD-1 led to complete tumor elimination without recurrence in 4T1-bearing mice (Fig. 3b–d).