NRG3 and schizophrenia: Importantly, numerous independent studies have identified a genetic association of natural variants of NRG1, NRG3, and ErbB4 with schizophrenia (Law et al., 2007; Kao et al., 2010; Greenwood et al., 2012; Joshi et al., 2014; Mostaid et al., 2016), as well as with altered electrophysiological properties of inducible pluripotential stem cells isolated from schizophrenia patients (Brennand et al., 2011).