A somatic mutation database reports 45 unique REXO2 mutations in a total of 47,818 tumour samples (https://cancer.sanger.ac.uk/cosmic/search?q=REXO2#), and 14 LoF germline REXO2 mutations have been reported in gnomAD (https://gnomad.broadinstitute.org/gene/ENSG00000076043). This evidence concerns the gene REXO2 and neoplasm.