In nearly 60% of all hereditary PCC cases, driver germline mutations have been detected in up to 20 genes, including MAX, NF1, RET, SDHA, SDHB, SDHC, SDHD, TMEM127, FH, VHL and others (Rattenberry et al., 2013, Martucci & Pacak, 2014, Buffet et al., 2018). The gene discussed is MAX; the disease is adrenal gland pheochromocytoma.