The t-test indicated that the KIF2C expression level in the relapse sample was significantly higher than that in the first-diagnosis sample in all cohorts (p-values: 1.977 × 10−4 in GSE28460, 8.945 × 10−5 in GSE60926, 1.497 × 10−5 in TARGET_paired sample and 1.232 × 10−11 in TARGET-ALL, Figure 1). Here, KIF2C is linked to acute lymphoblastic leukemia.