CASP3 and neoplasm: Furthermore, the growth rates of tumors formed from LNCaP cells expressing ADAMTS-15 was significantly reduced (Con: 0.058 ± 0.009 g/day; ADAMTS-15: 0.032 ± 0.006 g/day), while levels of the proliferation marker Ki-67 [49] in tumor sections showed revealed a similar decrease (Con: 25.6 ± 2.9%; ADAMTS-15: 18.8 ± 2.0%), whereas the apoptotic marker Caspase 3 [50] was not significantly altered.