Parallel to the changes in cell cycle progression, we observed a significant effect of IMP on the expression of genes (TP53, CDKN1A, and CCND1) coding for the key cell cycle regulatory proteins p53, p21Waf1/Cip1, and cyclin D1, respectively, in TE671 and RK33 cancer cell lines. The gene discussed is CDKN1A; the disease is cancer.