Regarding diabetes, VAT in non-pregnant adults is associated with 1) insulin resistance, which prevents glucose and additional fat from entering the cell and becoming preferentially oxidized; 2) glucose intolerance, with higher rates of insulin-stimulated glucose uptake compared with subcutaneous adipocytes; and 3) dyslipidemia, with greater lipolytic activity than subcutaneous adipocytes [24]. This evidence concerns the gene INS and diabetes mellitus.