The interaction between TRP120 and PCGF5 has been shown to occur in the nucleus during early infection (24 h) and with cytoplasmic morulae during late infection (72 h) [6]; however, TRP120 appears to interact with FBW7 in the nucleus throughout the course of infection resulting in Ub-mediated degradation of FBW7. Here, PCGF5 is linked to infection.