Through inhibition of PI3K/AKT signaling pathway, salidroside have been shown to repress proliferation, migration and invasion of human lung cancer cells [29], induce autophagy in human colorectal cancer cells [28] suppress LPS-induced myocardial injury [44] as well as attenuate Adriamycin-induced focal segmental glomerulosclerosis [45]. Here, AKT1 is linked to colorectal cancer.