RAC1 and cancer: 1A-116 Rac1 inhibitor showed antitumoral activity in vitro on a wide variety of cancer types such as breast cancer (Cardama et al., 2014a; Gonzalez et al., 2017), glioblastoma (Cardama et al., 2014b) and acute myeloid leukemia (Cabrera et al., 2017).