Of six lncRNA biomarkers, five lncRNAs biomarkers (LINC01697, LINC02487, LOC105376575, AC005083.1, and SLC8A1-AS1) seem to be tumor suppressors and downregulated in OSCC, while lncRNA U62317.1 tended to be an oncogene and up-regulated in OSCC (Figure 2B). This evidence concerns the gene SLC8A1 and neoplasm.