To search for potential biomarkers specific to MAS, we examined a group of 24 oncogenes or tumor related gene products detected by CNV analysis, and found that most of them, including BCL-2, CDKN2A, YWHAE, CCND1, HMGA2, KIF14, CDK4, and MDM2, were significantly overexpressed in MAS. The gene discussed is CDK4; the disease is neoplasm.