Furthermore, the present study carefully recorded basic data, risk factors, and laboratory information such as HR, SBP, DBP, EF, current smoking, hypertension, hyperlipidemia, type-2 DM, family history of CHD, fasting glucose, C-reactive protein, lipid profiles, creatinine, creatine kinase MB, and troponin I. Statistical analysis demonstrated that clinical characteristics among healthy groups and coronary artery disease patients were not influenced by miR-21 level in plasma, suggesting miR-21 as a potential biochemical biomarker for diagnosis of stable and unstable angina patients. This evidence concerns the gene CRP and coronary artery disorder.