HMGCR and Alzheimer disease: The relevant literatures also revealed that FGF1, FGF2, MAPT, CHRM2, CA2, CHRM1, STAT3, AR, CYP19A1, HSD11B1, NR1H3, HMGCR, ESR2, ESR1 and VDR may be involved in the pathogenesis of AD.