Certainly, a notable proportion of lncRNAs have also been found to regulate protein expression through ubiquitination: lncRNA uc.134 could repress hepatocellular carcinoma progression by inhibiting the CUL4A-mediated ubiquitination of LATS1 and increasing YAPS127 phosphorylation [40]. Here, CUL4A is linked to hepatocellular carcinoma.