Additionally, both erg1 and eag1 channel expression is aberrantly increased in a variety of tumor cells, where they increased cell proliferation level and tumor malignancy (Arcangeli et al., 2009; Pardo and Stühmer, 2014; Lastraioli et al., 2015; Prevarskaya et al., 2018). Here, KCNH1 is linked to neoplasm.