Upon IFN‐γ or TNF‐α stimulation, IL‐8, chemokine (C‐C motif) ligand 5 (CCL5) and CCL8 expression were significantly down‐regulated by miR‐124 whereas they were up‐regulated by IFN‐γ or TNF‐α.22 Taken together, miR‐124 regulates inflammatory responses in keratinocytes and chronic skin inflammation in AD through regulating the NF‐κB pathway, indicating that restoring miR‐124 expression may be a potential therapeutic strategy for AD. Here, CXCL8 is linked to Alzheimer disease.