NFKB1 and Alzheimer disease: In addition, it was demonstrated to directly target nuclear factor (NF)‐κB in B‐cell lymphoma.21 Yang et al investigated the role of miR‐124 in AD and showed that miR‐124 expression was down‐regulated in chronic AD skin lesions.22 MiR‐124 expression could also be strongly inhibited by IFN‐γ and tumour necrosis factor (TNF)‐α.