Recently, Balteau et al26 showed that in vitro glucagon‐like peptide 1 (GLP‐1) stimulated the α2‐isoform of AMPK and subsequently suppressed hyperglycemia‐stimulatedNox2 activation by limiting the protein kinase C (PKC)‐β2 phosphorylation andp47phox activation. Here, PRRT2 is linked to Hyperglycemia.