Thus, it can be speculated that also the remaining 13 genes (e.g. angiomotin like 1, Amotl1; proline rich 11, Prr11; or schlafen5, Slnf5 and Slnf8) may also be relevant and might be involved in metabolic diseases, which has to be evaluated in the future (Table 1). This evidence concerns the gene AMOTL1 and Other metabolic disease.