EGFR and cancer: For example, GO terms “stress response,” “DNA repair,” and “cancer-related signaling” (e.g., ERBB, NOTCH, and WNT) were unique to CRPC-Ad (Supplementary Fig. 6e), whereas “hormone transport” and “SC & development” were strongly associated with androgen-insensitive and CSC-enriched CRPC-NE (Supplementary Fig. 6f).