Within the gliomas of WHO grade II/III (IDHmut glioma and IDHwt glioma combined) subgroup, there was no difference in RPS27 mRNA expression between usually growing (infiltration into 1–3 lobes, mean expression 7.5-fold) and highly-diffuse tumors (infiltration into more than three lobes, mean expression 6.7-fold) (Figure 6c). The gene discussed is RPS27; the disease is central nervous system cancer.