These candidates that were more enriched in co-cultured CM (Co-CM) than prostate cancer cell CM (CTL CM) and fibroblast CM (FCM) were identified: C–C motif chemokine ligand 3/4 (CCL3/4), serpinE1, and urokinase-type plasminogen activator receptor (uPAR). Here, SERPINE1 is linked to prostate carcinoma.